Hello and welcome to the details of Large real world study confirms Pfizer Covid vaccine 94pc effective and now with the details
Subscribe to our Telegram channel for the latest updates on news you need to know.
WASHINGTON, Feb 25 — The Pfizer Covid-19 vaccine has proven 94 per cent effective in a study involving 1.2 million people in Israel, the first peer-reviewed real world research confirming the power of mass immunisation campaigns to bring the pandemic to a close.
The paper, which was published in the New England Journal of Medicine on Wednesday, also demonstrated there is likely a strong protective benefit against infection, a crucial element in breaking onward transmission.
“The fact that the vaccines worked so well in the real world... really does suggest that if the nations of the world can find the will, we now have the means to end Covid-19 forever,” said Ben Neuman, a virologist from Texas A&M University who was not involved in the research.
The experiment was carried out between December 20 2020 and February 1, 2021 — a period when a newer variant first identified in Britain was rampant in Israel, making the vaccine’s performance all the more impressive.
Around 1.2 million people were divided into equal groups of vaccinated and unvaccinated.
Each vaccinated participant was matched to an unvaccinated “control” person of similar age, sex, geographic, medical and other characteristics.
Lead author Noam Barda, head of epidemiology and research at the Clalit Research Institute, told AFP the matching process was highly robust.
An elderly Ultra-Orthodox Jewish man from a particular neighbourhood with a particular set of comorbidities and flu vaccination history would be matched for another person fitting that precise profile, for example.
The researchers then recorded outcomes at days 14-20 after the first of the two doses and day seven or more after the second.
The efficacy against symptomatic infections was 57 per cent between 14-20 days after the first dose, but rose to 94 per cent seven days after the second dose — very close to the 95 per cent achieved during Phase 3 clinical trials.
People who received second doses were also highly protected against hospitalisation and death — though the precise numbers here are less significant and had a wider statistical range because of the relatively lower number of cases.
The study also found people who received their second dose had a 92 per cent lower chance of getting any form of infection at all compared to those who were unvaccinated.
While this finding was considered encouraging, the researchers and outside experts said it needs more confirming evidence.
That’s because the participants weren’t being systematically tested at regular intervals; rather, they were getting a test when they wanted one.
The authors attempted to correct for this with statistical methods but the result is still likely imperfect.
“Unless you are testing everyone all the time, this will miss some infections,” said Natalie Dean, a biostatistician at the University of Florida.
She added she was certain there was a strong protective benefit, but “nailing down this number more precisely will require specialized study designs with frequent testing.” — AFP
These were the details of the news Large real world study confirms Pfizer Covid vaccine 94pc effective for this day. We hope that we have succeeded by giving you the full details and information. To follow all our news, you can subscribe to the alerts system or to one of our different systems to provide you with all that is new.
It is also worth noting that the original news has been published and is available at Malay Mail and the editorial team at AlKhaleej Today has confirmed it and it has been modified, and it may have been completely transferred or quoted from it and you can read and follow this news from its main source.